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血液病家族新成员——易栓症 被引量:5

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摘要 易栓症(tromobophilia)一词于1965年由Egeberg在报道一个家族性抗凝血酶(AT)缺陷症时首先提出^[1],意为血栓形成的倾向性增高。在相当一段时间内其成为遗传性抗凝功能缺陷的代名词,近些年来研究发现其发生多与机体的止凝血机制异常有关,故将其归类于血液病范畴。
作者 贺立山
出处 《医学新知》 CAS 2008年第3期129-132,共4页 New Medicine
关键词 血液病 易栓症
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参考文献15

  • 1Egeberg O. On the natural blood coagulation inhibitor system. Investigations of inhibitor factors based on antithrombin deficient blood[J].Thromb Diath Haemorrh, 1965,14(3-4):473-489.
  • 2Bertina R M, Koeleman B P, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C[J]. Nature, 1994,369(6475):64-67.
  • 3Tanaka Y, Ueda K, Ozawa T, et al. Intracellular accumulation of anti-thrombin Morioka C95R a novel mutation causing type Ⅰ anti-thrombin deficiency[J]. J Biol Chem,2002,27,277(52):51058-51067.
  • 4Svensson P J, Dahlback B. Resistance to activated protein C as a basis for venous thrombosis[J]. N Engl J Med, 1994,330(8):517-522.
  • 5Simmonds R E, Ireland H, Kunz G,et al.Identification of 19 protein S gene mutations in patients with phenotypic protein S deficiency and thrombosis[J]. Blood, Dec 1996, 88: 4195-4204.
  • 6Susan A M, Brian C, et al. Combined Tissue Factor Pathway Inhibitor (TFPI) and Thrombomodulin (TM) Deficiency Produces an Augmented Hypercoagulable State with Tissue Specific Fibrin Deposition[J].Blood (ASH Annual Meeting Abstracts),2007,110: 265.
  • 7Genser N, Lechleitner P, Maier J, et al. Rebound increase ofplasminogen activator inhibitor type 1 after cessation ofthrombolytic treatment for acute myocardial infarction is independent of type ofplasminogen activator used[J]. Clinical Chemistry, 1998,44:209-214.
  • 8Sugawara S, Nemoto E, Tada H, et al.Proteolysis of Human Monocyte CD14 by Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis Leading to Lipopolysaccharide Hyporesponsiveness[J]. The Journal of Immunology,2000,165:411-418.
  • 9Mammen E F. Ten years'experience with the"sticky platelet syndrome"[J]. Clin Appl Thromb Haemost,1995,1:66-72.
  • 10Sverre C, Christiansen, Suzanne C, et al. Vandenbroucke, and Frits R. Rosendaal. Thrombophilia, Clinical Factors, and Recurrent Venous Thrombotic Events[J].JAMA, 2005,293: 2352-2361.

二级参考文献4

  • 1Tatewaki H,Thromb Haemost,1999年,82卷,65页
  • 2王鸿利,血栓病学,1998年,342页
  • 3Andersen B D,Thromb Haemost,1996年,76卷,143页
  • 4包承鑫,血栓与止血基础理论与临床(第2版),1996年,466页

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二级引证文献35

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