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杜仲抗HIV gp41活性部位的研究 被引量:1

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摘要 目的:研究杜仲活性成分对HIV gp41六股螺旋束的抑制作用,为寻求新的抗HIV病毒进入抑制剂提供实验依据。方法:杜仲萃取物配制成1 mg/ml的样品液,用高效液相色谱法检测样品对HIV gp41六股螺旋束结构形成的抑制作用,并采用酚试剂法检测样品中鞣酸含量。结果:杜仲提取物浓度1 mg/ml可有效降低gp41峰高,1mg/ml的样品中含鞣酸10μg/ml。结论:杜仲可抑制HIV gp41六股螺旋束的形成,其有效成分可能不包括鞣酸。
出处 《中药材》 CAS CSCD 北大核心 2008年第5期726-729,共4页 Journal of Chinese Medicinal Materials
基金 国家自然科学基金(30500624) 广东省科技立项课题(2005A30101014) 广东省自然科学基金(7005187)
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