摘要
目的对常见女性不孕症的血清瘦素含量进行检测和分析,为临床诊断提供依据。方法采用放射免疫法检测187例不孕女性的血清瘦素含量,以正常生育女性50例做对照。结果卵巢功能障碍组、抗精子抗体阳性组、子宫内膜异位症组、正常生育对照组血清瘦素含量分别为21.14±2.52μg/L、17.39±3.02μg/L、20.77±2.36μg/L、12.05±2.01μg/L。卵巢功能障碍组、抗精子抗体阳性组、子宫内膜异位症组与正常生育对照组血清瘦素含量比较,均有显著性差异(P<0.01)。结论瘦素与卵巢功能障碍、抗精子抗体阳性、子宫内膜异位症等女性不孕症有密切关系。
Objective To detection and analyse the serum leptin level in female infertility. Methods： Serum leptin were detected by RIA in 187 cases of female infertility and 50 normal bearing female as control. Results： The level of leptin in ovarian dysfunction group, antisperm antibody positive group, endometriosis group and normal group were （21.14±2.52） μg/ L, （17.39 ± 3.02） μg/ L, （20.77±2.36） μ g/ L, and （12.05 ± 2.01） μg/ L respectively. Leptin concentration in the three groups was significantly increased as compared with the normal bearing group （P 〈0.01）. Conclusions： The high level of leptin has closely relations to ovarian dysfunction, antisperm antibody positive and endometriosis.
关键词
瘦素
女性不孕症
Leptin Female infertility
