摘要
目的 探讨哮喘患者外周血白细胞介素-13（IL—13）的变化及其在哮喘发病机制中的作用。方法 采用固相酶联免疫分析（ELISA）法检N30例支气管哮喘患者及25例正常对照组的血清IL—13的含量。结果 支气管哮喘急性期患者血清IL—13明显高于正常对照组（P〈0．01）。结论 IL—13参与支气管哮喘发病的病理生理过程，可为判断病情提供较好的实验室参数。
Objective To study the changes of peripheral blood interleukin（IL）-13 in the serum of asthma and their effect on the pathogenesis of asthma. Methods The serum level of IL-13 in 30 patients with acute asthmatic and 25 healthy controls were measured by ELISA. Results The serum level of IL-13 in acute asthma were significantly higher than those in healthy controls（P〈0.01）. Conclusions IL-13 might participate in the pathogenesis of asthma. The serum level of IL-13 can be the criteria for the changes in patient condition.
