术前介入治疗对1b2期宫颈癌近期疗效的观察

Short-term results of preoperative intra-arterial chemotherapy for cervical carcinoma in stage Ib2

目的研究巨块型宫颈癌Ib2期术前介入化疗加皿管栓塞的近期疗效。方法对我院收治的Ib2期宫颈癌患者56例，按术前治疗方法不同分术前介入化疗加血管栓塞联合后装放疗组（A组）及术前后装放疗组（B组），治疗后2—3周两组患者均行广泛全子宫加盆腔淋巴结清扫术。结果介化联合后装组的症状缓解率为100％，近期有效率达100％，单纯后装组的症状缓解率为100％，近期有效率为76．5％。两组的有效率和症状缓解率具有明显的差异（P〈0．05）。结论对于Ib2期宫颈癌患者，采用术前介入化疗联合放疗的方法可明显改善症状，提高宫颈癌的疗效。

Objective ： To study the effectiveness of intra-arterial chemotherapy before operation for bulky cervical carcinoma in stage Ib2. Methods： 56 cases divided into preoperative intra-arterial chemotherapy and radiotherapy group （A） and preoperative radiotherapy group （B）. Radical hysterectomy and lymphadenectomy was performed in each group 2-3 weeks after treatment. Result： The remission rate was 100% and the short-term effective rate was 100% in group A, while in group B were 52.9% and 76.5%. There＇s significant difference between two group （P〈0.05）. Conclusion： Intra-arterial chemotherapy and radiotherapy before operation can shrink tumor size and lessen symptoms, improve the curative effect.