超声造影对酒精注射治疗小肝癌疗效研究

Study to effect of percutaneous ethanol injection (PEI)for treatment of small hepatocellular carcinoma with Contrast enhanced Ultrasonography

目的应用超声造影对彩超引导下酒精介入治疗小肝癌疗效进行研究。方法应用彩色超声引导无水酒精注射治疗8例小肝癌,每周1次,1个月后应用超声造影检查。结果所有病例治疗后1个月应用超声造影,其中6例肿块内血流消失,各个时相呈无回声增强。2例肿块内血流减少,未灭活部分动脉相高回声增强,门脉相及延迟相低回声增强,灭活部分呈无回声增强。病人治疗后全身情况好转,症状减轻或消失,AFP和肝功能改善,无严重并发症发生。结论超声引导酒精介入治疗对小肝癌的治疗有较好的疗效,安全实用,超声造影有助于判断无水酒精注射治疗的疗效。

[Objective] To study therapeutical effect of CDFI guided percutaneous ethano injection （PEI） for treatment of small hepatocellular carcinoma （HCC） with Contrast enhanced Ultrasonography. [Methods] With the US guidance, 8 patients with HCC underwent PEI therapy. Once a week, ethanol was slowly injected into the center of tumors through a skinny needle. Contrast enhanced Ultrasonography was applied after 1 month. [Results] 8 patients were observed with Contrast enhanced Ultrasonography After 1 month treatment, the blood flow of tumours in 6 patients di-sappear, There was no enhancement in the tumors all phases, the blood flow were decreased in 2 patients, There was no enhancement in the inactivation part of tumours, the high-echo enhancement is showed in activation part of tumours in arteria phases, low-echo enhancement is appeared in portal phases and delay phases. All patients were in a good condition. They showed relief or disappearance of the symptom, the improvement in AFP and liver function, without serious complication. [Conclusions] US guided PEI is an effctive, safe and practical method for small HCC. Contrast enhanced Ultrasonography may be valuable in evaluating of PEI.