期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

氯取代二苯基苯甲酰基吡唑酮席夫碱的合成与抑菌活性 被引量：2

Synthesis and antibacterial activities of chloro-substituted diphenylbenzoylpyrazolone and its Schiff bases
下载PDF
导出
摘要 In this paper,an unreported novel acylpyrazolone——1-(p-Cl-phenyl)-3-phenyl-4-benzoyl-pyrazolone-5(CPPBP) and its five Schiff bases have been synthesized in the nonaqueous solvent.Their molecular structures are characterized by the elemental analysis,IR,MS and 1H NMR and an elementary antibacterial activity experiment is made.The results of structural characterization show that CPPBP exist in ketoform structure mainly and other five compounds S1,S2,S3,S4 and S5 coexisted in ketoform and enolform structure after forming the schiff bases.The antibacterial avtivity experiment indicat that six compounds are resistant to four different bacteria with various degrees. In this paper, an unreported novel acylpyrazolone 1-（ p-Cl-phenyl ）-3-phenyl-4-benzoyl - pyrazolone-5 （CPPBP） and its five Schiff bases have been synthesized in the nonaqueous solvent. Their molecular structures are characterized by the elemental analysis, IR, MS and I H NMR and an elementary antibacterial activity experiment is made. The results of structural characterization show that CPPBP exist in ketoform structure mainly and other five compounds S1, S2, S3, S4 and S5 coexisted in ketoform and enolform structure after forming the schiff bases. The antibacterial avtivity experiment indicat that six compounds are resistant to four different bacteria with various degrees.
作者 俞志刚 李东颖 颜婉茹
机构地区 哈尔滨理工大学化学与环境工程学院
出处 《化学研究与应用》 CAS CSCD 北大核心 2008年第5期596-599,共4页 Chemical Research and Application
基金 哈尔滨市青年科学基金(2005AFQXJ071)资助项目
关键词 吡唑酮席夫碱 合成 抑菌活性 pyrazolone Schiff base synthesis antibacterial activity
分类号 O614.33 [理学—无机化学] O626.21 [理学—有机化学]
  • 相关文献

参考文献15

  • 1A.Jyothi,G.N.Rao.Solvent extraction behaviour of lanthanum(Ⅲ),cerium(Ⅲ),europium(Ⅲ),thorium(Ⅳ) and uranium(Ⅵ) with 3-phenyl-benzoyl-5-isoxazolone[J].Talanta,1990,37(4):431-433.
  • 2I.L.Dukov,V M Jordanov.Synergistic solvent extraction of lanthanides with mixtures of 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone and primary ammonium salts[J].Hydrometallurgy,1998,48:145-151.
  • 3杜家声.4,4'-癸二酰-双-(1-苯基-3-甲基-5-吡唑啉酮)和中性磷萃取剂对铀(Ⅵ)的协同萃取[J].化学研究与应用,1992,4(1):65-69. 被引量：8
  • 4Hiroshi Mukai,Shoji Miyazaki,Shigeo umetani,et al.Synergic liquid/liquid extraction of lithium and sodium with 4-acyl-5-pyrazolones with bulky substituents and tri-n-octylphosphine oxide[J].Analytica chimica acta,1989,220:111-117.
  • 5M I Saleh,M Ahmad,H Darus.Solvent extraction of lanthanum(Ⅲ),europium(Ⅲ) and lutetium(Ⅲ) with fluorinated 1-phenyl-3-methyl-4-benzoyl-5-pyrazolones into chloroform[J].Talanta,1990,37(7):757-759.
  • 6Dejian Zhou,Qin Li,Chunhui Huang,et al.Room-temperature fluoresecnce,phosphorescence and crystal structure of 4-acyl pyrazolone lanthanide complexes:Ln(L)3·2H2O[J].Polyhedron.,16(8):1381-1389.
  • 7Jun Li,Li Zhang,Lang Liu,et al.A series of pyrazolone lanthanide(Ⅲ) complexes:synthesis,crystal structures and fluorescence.[J].Inorganic Chimica Acta,2007,360:1995-2001.
  • 8Miguel F Brana,Ana Gradillas,Angel G Ovalles,et al.Synthesis and biological activity of N,N-dialkyamino-alkyl-substituted bisindolyl and diphenyl pyrazolone derivatives[J].Bioorganic & Medicinal Chmistry,2006,14(1):9-16.
  • 9何其庄,马树芝,许东芳.稀土酰基吡唑啉酮邻菲咯啉配合物的合成、表征及其生物活性[J].无机化学学报,2007,23(10):1723-1728. 被引量：41
  • 10李锦州,张光林,沙靖全,安郁美.呋喃甲酰基吡唑啉酮缩氨基硫脲配合物的合成、光谱表征及生物活性[J].光谱学与光谱分析,2005,25(2):216-218. 被引量：12

二级参考文献44

共引文献67

同被引文献22

  • 1张欣,朱华玲,徐海珍,王瑾玲.1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮(HPMBP)缩甘氨酸甲酯的合成、表征和晶体结构[J].有机化学,2004,24(2):195-198. 被引量：8
  • 2王瑾玲,丁峰,郁铭.1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮与对氨基苯乙酮的缩合反应、量化计算和抑菌活性[J].有机化学,2004,24(11):1423-1428. 被引量：14
  • 3段长强 孟庆芳 张泰.现代化学试剂手册(第一分册)[M].北京:化学工业出版社,1986.282.
  • 4]Dukov I L,Jordanov V M. Synergistic solvent extraction of lanthanides with mixtures of 1-phenyl-3-methyl-4-benzoyl- 5-pyrazolone and primary ammonium salts [ J ]. Hydromet- allurgy, 1998,48 : 145-151.
  • 5I Jsdejaa R N, Parihara S, Vyasa K, et al. Synthesis and crystal structure of a series of pyrazolone based Schiff base ligands and DNA binding studies of their copper comple- xes[ J]. J Mol Stru,2012,1013 ( I 1 ) :86-94.
  • 6Maurya R. C. , Rajput S. Oxovanadium ( IV ) complexes of bioinorganic and medicinal relevance : synthesis, character- ization and 3D molecular modeling and analysis of some oxovanadium( IV ) complexes involving the O, N-donor en- vironment of pyrazolone-based sulfa drug Schiff bases [ J ]. J Mol Stru,2006,794(1-3) :24-34.
  • 7Zhang Y H, Zhang L, Liu L, et al. Anticancer activity, structure, and theoretical calculation of N-( 1-phenyl-3- methyl-4：propyl-pyrazolone-5)-salicylidene hydrazone and its copper ( /I ) complex [ J ]. lnorganica Chimica Acta, 2010,363(2) :289-293.
  • 8Listkowski A, Osinska W, Mohanraj J, et al. Synthesis and photoluminescence properties of novel lanthanide comple- xes based on pyrazolone Schiff bases[J]. Syn Met,2012, 1'62(13-14) :1 285-1 291.
  • 9Li J,Zhang L, Liu L, et al. A series of pyrazolone lantha- nide( 11I ) complexes: Synthesis, crystal structures and fluo- rescence [ J ]. Inorganic Chimica Acta, 2007,360 : 1 995-2 001.
  • 10Isaad J. Highly water soluble dyes based on pyrazolone de- rivatives of carbohydrates [ J ]. Tetrahedron,2013,69 (10) : 2 293-2 250.

引证文献2

二级引证文献6

化学研究与应用
2008年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部