期刊文献+

高同型半光胱氨酸血症与脑血管病及干预治疗

下载PDF
导出
摘要 1969年,McCully首次报道1例少见的遗传型同型半胱氨酸血症的病例,意外地发现同型半胱氨酸(homocysteie,Hcy)与动脉粥样性病症具有相关性。随着近年来到Hcy和脑血管关系的不断深人研究,Hcy在动脉粥样硬化发展中的重要性已经引起重视,目前认为Hcy是粥样硬化及冠心病、脑血管的独立危险因素之一。现将近年来有关研究进展综述如下。
作者 胡冬梅
出处 《中国医药指南(学术版)》 2008年第9期69-70,共2页 Guide of China Medicine
  • 相关文献

参考文献5

二级参考文献31

  • 1沈佐君,吴琳.高效毛细管电泳法快速测定血清中游离氨基酸[J].中华检验医学杂志,1998,22(3):22-25. 被引量:22
  • 2Refsum H, Fiskerstrand T, Guttormsen AB, et al. Assessment of homocysteine status. J Inherit Metab Dis 1997, 20 : 286- 94.
  • 3Hankey GJ,Eikelboom JW. Homocysteine and stroke. Curr Opin in Neurol, 2001,14 : 95- 102.
  • 4Brattstrom Let al. Hyperhomocysteinemia in stroke: prevalence,cause and relationships to type of stroke and stroke risk factors.Eur Clin Invest, 1992,22:214-21.
  • 5Mujumdar VS,Hayden MR, Tyagi SC. Homocysteine induces calcium second messenger in vascular smooth muscle cells. J Cell Physiol,2000,183:28:-36.
  • 6Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature, 1993:362: 801- 9.
  • 7Chao CL, Kuo TL, Lee YT. Effects of methionine-indueed hyperhomocysteinaemla on endothelium - dependent vasodilation and oxidative status in healthy aldults. Circulation, 2000, 101: 485-90.
  • 8Chambers JC, Obeid OA, Kooner JS. Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects. Arterioscler Thromb Vase Biol, 2000, 20: 185-88.
  • 9Ling O, Hajjar KA. Inhibition of endothelial cell thromboresistance by homocysteine. J Nutr, 2000,130 (suppl) : S373- S376.
  • 10Dardik R, V aron D, Tamarin I,et al. Homocysteine and oxidized low density lipoprotein enhances platelet adhesion to endothelial cells under flodiw conditionsL distinct mechanisms of thrombogenic modulation Thromb Haemost, 2000, 83 : 338- 44.

共引文献108

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部