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非典型川崎病的早期诊断

Early diagnosis of atypical kawasaki disease
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摘要 目的通过对非典型川崎病的临床分析而提高对其认识,利于早期诊断。方法对21例非典型川崎病患儿的临床资料进行回顾性分析并进行统计学比较。结果皮疹、球结膜充血、口唇干裂发生率高,手足硬肿及淋巴结肿大发生率较低,血白细胞、中性粒细胞、C-反应蛋白升高、血沉增快发生率高,尚需注意尿常规异常、贫血、肝功能异常等多系统损害。结论发热≥5d、应用抗生素无效,具备2~3项主要诊断标准结合心脏彩超、实验室检查综合分析,作出早期诊断。 Objective To analyze the clinical features of atypical kawasaki disease, so as to provide reference for its early diagnosis. Methods Clinical data of 21children suffering from atypical kawasaki disea,se was retrospectively analyzed and statistically treated. Results The incidence of rash, bulbar conjunctival congestion and cheilosis was high, whereas erythema and edema of extremity, lymphadenectasis were infrequent. The incidence of leukocytosis, neutrophilic leukocytosis, thrombocytosis, erythrocyte sedimentation rate elevation and C-reactive protein increase was high. In addition, multiple organ damage including urine abnormity, anemia, liver function abnormity and hypoalbuminemia needed to be attended. Conclusion Patients of fever persisting for at least 5 days, antibiotic inefficacy and having 2-3 principal features should be synthetically analyzed with echocardiography and laboratory examination, so as to attain the goal of early diagnosis.
作者 刘益 杜宜秀
出处 《中国医药指南(学术版)》 2008年第10期25-26,共2页 Guide of China Medicine
关键词 川崎病 非典型 诊断 儿童 atypical kawasaki disease diagnosis children
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