慢性功能性便秘肛管直肠动力学的临床研究

Anorectal Manometry in patients with Chronic Functional Constipation

目的:研究慢性功能性便秘患者的肛管直肠动力学改变。方法:采用低顺应性水灌注式测压系统,以静止测压法进行肛管直肠测压,测定20例患者和15例健康人的肛门直肠压力,测定直肠对容量刺激的最低敏感量、最大耐受量及直肠顺应性。结果:患者的直肠、肛门内外括约肌静息压力以及内括约肌主动收缩压、模拟排便时直肠收缩压、内外括约肌净减压与对照组比较无显著性差异。肛门直肠屏障压高于对照组,直肠对容量刺激的最大耐受量及顺应性均高于对照组。结论:慢性功能性便秘患者存在肛门直肠动力学异常,便秘发病可能与直肠的低敏感及高耐受感觉有关,这种异常可能是导致便秘的原因之一。

Objective To study the anorectal motility in patients with chronic functional constipation （CFC）. Methods Rectal visceral thresholds, rectal compliance and anorectal manometry were examined in 20 perceptive patients with functional constipation and in 15 healthy adults as controls. Results The anorectal resting pressure, relaxation pressure had no significant difference between the two groups. Anorectal barrier pressure in CFC was higher than thatin healthy control group（76.90 ± 23.28, 66.80 ± 21.36, respectively）. The maximum tolerance of the rectum and rectal compliance in CFC were higher than that in controls （P 〈0.01 ）. Conclusion There were anorectal motility abnormalities in functional constipation, which might contribute to the symptom of constipation.