摘要
目的探讨桔梗皂苷D的HPLC法制备方法。方法采用超声提取方法,通过大孔吸附树脂得到各水相、有机相,再根据不同分离原理,运用硅胶、ODS、HPLC等柱层析技术对桔梗总皂苷及其单体皂苷进行分离,制备桔梗皂苷D,优化其工艺。结果和结论该制备方法先进、简便、省时、效率高。
Objective The mass-manufacture technology of the total saponin and the crystal saponin of Platyeodi Radix were studying in this paper. To explore the roots of Platycodon grandiflorum A.DE. Methods Candolle were extracted with distilled water by means of ultrasonic method,and the mass-manufacture technology of the total saponin and the crystal saponin were optimitized ,which were isolated by using the column chromatographical technique of macroporous adsorption resin silca gel, ODS, HPLC, etc. Results ultrasonic method were obtained. Conclusion Fourteen crystal compounds were obtained, and platycodin-D was mainly identified and prepared.
出处
《中外医疗》
2008年第15期98-99,共2页
China & Foreign Medical Treatment
