肝脏局灶性结节性增生的诊断与治疗

Diagnosis and treatment of hepatic focal nodular hyperplasia

目的:探讨肝脏局灶性结节性增生(focal nodular hyperplasia,FNH)的临床诊断和治疗。方法:回顾性分析19例经病理组织学检查确诊的FNH的临床病理、影像学检查、外科治疗及随访资料。结果:19例FNH,影像学检查诊断率较低,其中彩超确诊率42.1%(8/19),CT57.9%(11/19),MRI75.0%(12/16),手术切除病灶效果好,随访1年未发现复发病例。结论:目前CT和MRI是FNH诊断的重要手段,对影像检查疑为FNH又暂不同意手术探查病人可考虑定位穿刺活组织检查,但对穿刺未能定性成功及不能排除恶性肿瘤者应手术治疗。

Objective： To evaluate the clinical diagnosis and treatment of focal nodular hyperplasia of the liver. Methodsz Retrospective analysis was made on 19 cases with surgical and pathological proved FNH. The clinical and pathological data were reviewed. Result： To 19 FNH patients, The preoperative radiography was usually not specific, The correct diagnostic rate of BUS, CT and MRI was 42.1% ,57.9% and 75.0%, respectively. Surgical resection resulted in a permanent cure with no significant postoperative complications and without recurrence at one year follow-up. Conclusions： CT and MRI are important for the diagnosis of FNH. Liver biopsies and surgical resection can be performed on cases with equivocal diagnosis、symptom or in fear of hepatic malignancy.