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婴幼儿巨细胞病毒感染致类白血病反应7例分析 被引量:6

Clinical analysis of leukemoid reaction in infants and young children with CMV infection
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摘要 目的探讨儿童巨细胞病毒(CMV)感染致类白血病反应的临床特点。方法对四川大学附属华西第二医院儿童血液科所收治的7例CMV感染后致类白血病反应患儿的临床资料,进行回顾性分析。结果7例患儿中6例婴儿,临床上多有发热、出血、贫血、肝脾淋巴结肿大等表现,外周血白细胞明显升高,出现幼稚细胞,抗CMV-IgM(+),CMV-IgG(-),骨髓检查正常或未达白血病诊断标准,经更昔洛韦抗病毒治疗疗效满意,多数患者恢复良好,血象和骨髓象恢复正常。结论婴幼儿CMV感染可能是类白血病反应病因之一,临床上类似血液肿瘤性疾病,应结合临床表现和有关实验室检查综合分析鉴别,对疑难病例应密切观察和长期随访。
出处 《临床儿科杂志》 CAS CSCD 北大核心 2008年第6期476-479,共4页 Journal of Clinical Pediatrics
关键词 巨细胞病毒 类白血病反应 婴幼儿 cytomegalovirus leukemoid reaction infants and toddlers
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