期刊文献+

儿科综合性医院结核病发病情况分析 被引量:7

Investigation of tuberculosis disease in a pediatric hospital
下载PDF
导出
摘要 目的通过调查分析儿童结核病在非结核病专科的儿科医院的发病情况,进一步探讨儿童结核病的发病特点。方法收集近九年收住的出院诊断为结核病的患者病史,并进行重新评估,对符合诊断的103例患儿的临床资料作回顾性分析。结果结核病诊断率增加,以7~14岁年龄段发病率较高(占35.92%);19.2%有明显的结核病接触史,主要集中在4岁以下的儿童,传染源多为日常密切接触的家人;28%患儿结核菌素试验阴性,其结核类型主要为粟粒型肺结核、结核性脑膜炎等,中、重症结核病表现多见;结核病患儿中出现发热、咳嗽等症状者仅50%左右。结论我国儿童结核病流行趋势严峻,各年龄段发病率不同,结核病患儿的临床表现多样化,临床诊断手段匮乏,需要进一步加强研究。 Objectives To retrospectively investigate the epidemiology and incidence of tuberculosis in a pediatric hospital, and to further study the characteristics of tuberculosis in children. Methods Clinical data of 103 children with tuberculosis were reviewed. Results The incidence was highest in patients aged between 7 and 14 years (35.92%). 19.2% had contact with patients with active tuberculosis, most of them were the children younger than 4 years. The sources of the infection were the parents and relatives. PPD test was negative in 28% of the severely infected patients, such as miliary tuberculosis, tuberculous meningitis. Only half of the patients developed fever and cough. Conclusions The prevalence of tuberculosis in children is still high in China, and their clinical manifestations could be atypical. Diagnosis of tuberculosis requires methods with higher specificity and sensitivity.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2008年第6期486-489,共4页 Journal of Clinical Pediatrics
关键词 儿童 结核病 流行病学 childven tuberculosis epidemiology
  • 相关文献

参考文献8

二级参考文献19

  • 1Mason CM, Ali J.lmmunity against mycobacteria.Semin Respir Crit Care Med, 2004, 25(1): 53-59.
  • 2Aubert-Pivert EM, Chedevergne FM, Lopez-Ramirez GM, et al.Cytokin transcripts in pediatric tuberculosis, a study with bronchoalveolar cells.Tuber Lung Dis, 2000, 80(6): 249-258.
  • 3Starke JR.Tuberculosis in children.Respir Crit Care Med, 2004, 25(3): 353-354.
  • 4Dannenberg AM.Macrophage turnover, division and activation with developing peak and healed tuberculous lesion preduced in rabbits by BCG.Tuberculous, 2003, 83(4): 251-260.
  • 5Lalvani A.Spotting latent infection: the path to better tuberculosis control.Thorax, 2003, 58(11): 916-918.
  • 6Nuermber E, Bishai WR, Grosset JM.Latent tuberculosis.Semin Respir Crit Care Med, 2004, 25(3): 317-333.
  • 7Miller FJW, Seal RME, Tayor MD, et al.Tuberculosis in children.In: Churchill Ltd.lst ed.London, 1963.44.
  • 8范永琛.原发肺结核钙化淋巴结所致之长期发烧[J].天津医药,1978,12:550-552.
  • 9Behrman RE, Kliegman RM, Jenson HB.Textbook of pediatrics.16th ed.Philadelphia: W.B.Saunders Co, 2000.886.
  • 10Mandell GL, Bennelt JE, Dolin R.Infections diseases. 5th ed.Harconut Asia Churclill Livengstone Singapore, 2001.2582.

共引文献139

同被引文献55

引证文献7

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部