无心畸形胎儿3例临床病理分析

Acardia fetus:a clinicopathologic study of 3 cases

目的观察无心畸形胎儿的临床病理形态,并对其发生进行分析。方法对3例无心畸形胎儿的临床表现、外形和内脏结构以及胎盘形态进行观察与分析。结果3例无心畸形胎儿分别来自双胎与三胎妊娠,2例无头,均为单体腔,可见发育不良的肠管以及肾上腺,其它脏器为:肾脏2例,性腺与内生殖器2例,心脏胚基1例,肝脏胚基1例。胎盘为单绒毛膜型,2例有大血管吻合与单脐动脉。结论无心畸形胎儿有多种形态,其发生与双胎胎盘的血管吻合有密切关系。

Purpose To observed the clinicopathologic features of acardia, and to investigate the pathogenesis of acardia. Methods 3 cases of aeardia were observed with analyses of clinical features, their externalities and the structures of viscera and placentas. Results 3 cases of acardia were from twins or triplets, and 2 were acephalus. All of the 3 cases were mono-coelome, there were hypogenetie intestines and adrenal gland. Other viscera included kidney in ：2 cases, gonad and sex organs in 2 cases, heart radicle and liver radicle in 1 case. All of the placentas were in monochorial type, two of them had dominant anastomoses and single umbilical artery. Conclusions The various morphology of acardia could be observed. The pathogenesis of acardia may be related with the anastomoses of the placenta.