戈登链球菌的生物学特性及在黏膜疫苗的应用

The Bionomics of Streptococcus gordonii and Its Application in Mucosa Vaccine

戈登氏链球菌是一种非致病性革兰氏阳性黏膜共生菌,参与组成人类口腔正常菌群。它具有特殊的生物学特性,非常适合作为黏膜疫苗的载体。了解戈登氏链球菌的生物学特性,常用表达体系及该菌在黏膜疫苗的应用情况,将为其黏膜疫苗的进一步研制提供重要参考。

Streptococcus gordonii is a nonpathogenic gram-positive commensal bacterium and component of the normal microbial flora of the human oral cavity. It is suitable to be as a mucosa vaccine vector due to its special bionomics, knowing the bionomics of Streptococcus gordonii, the general expressing system, and the application of it in mucosa vaccine, will provid important reference for the further development of its mucosa vaccine.