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谷胱甘肽转移酶π在乳腺癌中的表达及其临床意义

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摘要 目的探讨乳腺癌组织中谷胱甘肽转移酶(GSTpi)的表达与预后的关系。方法用免疫组化方法检测120名女性乳腺癌患者GSTpi的表达情况,并与患者年龄、肿瘤大小、组织学分级、腋淋巴结转移及临床分期进行相关分析。统计学:采用χ2检验,相关性检验采用秩相关统计法。结果谷胱甘肽转移酶(GSTpi)的表达与乳腺癌肿瘤大小、组织学分级及腋淋巴结转移率、临床分期密切相关(P<0.05)。结论谷胱甘肽转移酶(GSTpi)与乳腺癌预后关系密切。乳腺癌组织中GSTpi的存在是一个预后差的预后指标。
作者 吉庆明
机构地区 河南省胸科医院
出处 《临床医学》 CAS 2008年第5期113-114,共2页 Clinical Medicine
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