疏血通注射液治疗糖尿病伴冠脉支架术后心绞痛疗效评价

Clinical Observation of the Effect of Shuxuetong Injection on Unstable Angina Pectoris in Diabetic Patients after Coronary Stent Implantation

目的:研究疏血通注射液治疗糖尿病伴冠状动脉支架置入术后不稳定型心绞痛的临床疗效。方法:将40例冠状动脉支架置入术后的糖尿病不稳定型心绞痛患者随机分为两组。在冠心痛糖尿病常规治疗基础上,对照组17例给予丹参酮注射液6 ml,治疗组23例给予疏血通注射液6 ml,各溶入0.9%氯化钠注射液250 ml,ivd qd,15 d为1个疗程。观察两组治疗前后心绞痛发作频率、心肌缺血程度、血浆纤维蛋白原(FBG)含量、血清C反应蛋白(CRP)含量。结果:治疗组在减少冠心痛心绞痛发作频率,改善心电图心肌缺血等方面均显著优于对照组(P<0.05),血FBG、CRP水平明显下降(P<0.05)。结论:疏血通注射液能明显缓解糖尿病伴冠脉支架术后心绞痛患者的临床症状,有效抑制血栓的形成和炎症反应。

Objective： To observe the effect of Shuxuetong Injection on unstable angina pectoris in diabetic patients after coronary stent implantation. Method： 40 diabetic patients after coronary stent implantation were randomly divided into two groups. The patients in the two groups were treated with basic drugs. 17 patients in the controlled group were venously treated with Danshen injection 6 milliliters dissolved in 250 milliliters 0.9% sodium chloride injection once daily. 23 patients in the treatment group were venously treated with Shuxuetong injection 6 milliliters dissolved in 250 milliliters 0.9% sodium chloride injection once a day, The treatment course was Fifteen days in both groups. The clinical effect and the frequency of angina attack were observed in both groups. The concentrations of plasma fibrinogen （FBG） and serum Creactive protein （CRP） were measured before and after the treatment. Result： Compared with those of the controlled group, the frequency of angina attack and the indication of myocardial ischema in electrocardiogram greatly improved（ P 〈 0.05 ） in the treatment group, and the plasma FBG and serum CRP concentration decreased significantly （ P 〈 0.05 ）. Conclusion： Shuxuetong injection has a definite effect on unstable angina pectoris in diabetic patients after coronary stent implantation, and can actively suppress thrombogenesis and inflammatory reaction.