摘要
目的前瞻性单盲研究无痛人工流产术后用佳苏伦对患者苏醒质量的影响。方法将60例接受无痛人工流产的患者随机分为甲、乙两组:甲组人工流产结束后静注佳苏伦(盐酸多沙普伦)1 mg/kg,乙组注入等容量生理盐水作对照。由不知所用何药的人流室护士观察并记录用药前及随后1、3、5、10 min患者的呼吸频率及幅度、血氧饱和度(SpO2)、清醒时间及苏醒期并发症。结果甲组患者的清醒和留观时间明显缩短,呼吸频率和幅度明显增加,心率(HR)、SpO2显著提高,血压(BP)变化差异无统计学意义。结论无痛人工流产结束后用佳苏伦可安全地改善患者的苏醒质量,缩短留观时间。
Objective To investigate the effect of doxapram who undergoing on recovery times after painless induced abortion by randomized, single blind controlled trial.Methods Sixty patients received painless induced abortion were randomly allocated to receive either doxapram hydrochloride 1 mg/kg iv or saline placebo.The respiratory,pulse,SpO2,NIBP, recovery times and complications were assessed at 1,3,5,10 min by a nurse who didn＇t know whether doxapram or saline placebo had been used.Results Recovery time was shorter in the doxapram group compared with the control group [（2.7±0.7）min vs（6.9±3.4） min,P〈0.01）].A greater increase in heart rate and SpO2 with doxapram（P〈0.05 compared with placebo）,but no difference in systolic blood pressure responses was observed in comparison with placebo.Conclusion We conclude that doxapram 1 mg/kg hastens early recovery from painless induced abortion and shorten the recover times.
出处
《临床医学》
CAS
2008年第6期27-28,共2页
Clinical Medicine
