散瘀消肿膏抗炎镇痛药效学试验

Studies on the anti-inflammatory and analgesic effects of the sanyuxiaozhong ointment

目的研究不同浓度散瘀消肿膏的抗炎镇痛作用。方法抗炎作用试验采用小鼠耳肿胀法和大鼠足爪肿胀法;镇痛作用试验采用小鼠热板法及光辐射热甩尾法。结果中浓度散瘀消肿膏对小鼠二甲苯性耳肿胀及大鼠角叉菜胶性足跖肿胀有明显的抑制作用;对小鼠热板法和甩尾法致痛均有明显的镇痛效果。结论中浓度散瘀消肿膏具有明显的抗炎镇痛药效。

Objective To study anti - inflammatory and analgesic effects of the sanyuxiaozhong ointment. Methods Different anti - inflammatory and analgesic models were made to investigate the anti - inflammatory and analgesic effects of the sanyuxiaozhong ointment. Results The resulted of the anti - inflammatory experiments showed that ear edema resulted from dimethyl benzene and paw edema induced by carrageenan were significantly inhibited by the sanyuxiaozhong ointment;and the sanyuxiaozhong ointment also produced obvious analgesic effects on the analgesic model of light - heat stimulation in mice. Conclusion The Sanyuxiaozhong ointment has significant anti -inflammatory and analgesic effect.