摘要
目的观察骨痹汤治疗幼年强直性脊柱炎肾虚湿热证的疗效和安全性。方法将60例患者随机分为两组,治疗组服骨痹汤,对照组服柳氮磺胺嘧啶,疗程26周;比较两组症状、体征和检验指标改善情况。结果治疗组在BASFI指数、关节肿积分、附着点痛积分、骶髂CT影像学改变明显优于对照组,且未见明显毒副作用。结论骨痹汤治疗幼年强直性脊柱炎肾虚湿热证安全有效。
Objective: The efficacy and safety of Gubi Decoction were evaluated for the renal deficiency and damp- heat syndrome of juvenile ankylosing spondylitis. Methods: The patients were divided into two groups randomly. The treatment group ( n = 30) used Gubi Decoction. The control group( n = 30) used salicylazosulfapyridine. Both groups were treated for 26 weeks. Clinical symptom, physical sign and chemical examination were record- ed. Results: The treatment group showed significant improvements in the following points: BAS function index, joint - swelling index and enthesis index of the treatment group were improved more than the controll group. The CT alteration of sacroiliac articulation of treatment group was better than the control group. Conclusion: Gubi Decoction is an effective and safe therapy for juvenile ankylosing spondylitis of the renal deficiency and damp - heat syndrome.
出处
《中国中医急症》
2008年第6期772-774,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
北京中医药科技发展基金项目(No.JJ2003-22)
关键词
幼年强直性脊柱炎
肾虚湿热证
中医药疗法
骨痹汤
Juvenile ankylosing spondylitis
Renal deficiency and damp -heat syndrome
Traditional Chinese medicine therapy
Gubi Decoction