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代谢综合征患者心率变异性、亚临床炎症和心室重构的临床研究——附58例报告 被引量:1

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摘要 目的:探讨代谢综合征(metabolic syndrome,MS)患者心率变异性(heart rate variabili-ty,HRV)的改变及其与炎症标志物、心室重构的关系。方法:分别测定58例MS患者(MS组)和20名健康人(对照组)的血浆超敏CRP、TNF-α和白介素-6,行24h动态心电图监测,了解HRV的频域指标(低能谱、高能谱和低能谱/高能谱);行UCG检查,根据其结果计算左心室质量指数(left ventricular mass index,LVMI)。结果:与对照组比较,MS患者HRV指标下降、炎症指标升高和LVMI、室间隔舒张末期厚度增加(P<0.05~0.01)。在左心室肥厚组,其HRV改变表现以高能谱异常为著。直线相关分析结果显示,HRV频域指标与炎症水平和左心室重构明显相关(P<0.05~0.01)。结论:MS患者存在HRV下降、炎症指标升高和左心室重构现象。MS患者亚临床炎症程度与HRV指标下降有关,心室重构的程度与HRV指标改变基本一致。
出处 《新医学》 北大核心 2008年第6期382-384,共3页 Journal of New Medicine
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参考文献7

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