尿激酶静脉溶栓治疗老年急性心肌梗塞

VENA THROMBOLYSIS TREATING SENILE ACUTE MYOCARDIAL INFARCTI ON WITH UROKINASE

选同期入院的老年急性心肌梗塞（ＡＭＩ）患者２４例，分为对照组１４例和尿激酶（ＵＫ）静脉溶栓组１０例；进行临床对比观察。结果：在缩小ＡＭＩ范围及改善心功能方面溶栓组优于对照组，两组具显著差异性（Ｐ＜０．０５）；５周病死率溶栓组１０％低于对照组２１％；溶栓组再通率６０％与国内报道链激酶静脉栓再通率６６．６％相近；溶栓后再闭塞率１０％比国外报道１２％略低；溶栓后发生轻度出血占２０％。结论是：只要严格选择病例，防止出血等并发症的发生，ＵＫ静脉溶栓治疗老年ＡＭＩ是安全有效的。

In order to obserive and contrast treatment effect 24cases selected senile acute myocardial infatction(AMI)Patients who are inhospital homochronously are divided by routine group contral group,14cases and Urokinase Vena thrombolysis group 10cases The results show as follow;about Shrinking AMI range and improving heart function,the treatment effect of thrombolysis group is superior which is obvious difference(P〈0 05);5week death ratio(10%)is lower than contral group′s(21%);the recirculation ratio of thrombolysis group(60%)is near to streptokinase′s(66 6%)which has been reported in our country;after thrombolysis the reembolism ratio(10%)is lightly lower than the over sea′s(12%);the complication,lightly bleeding,is20%after thrombolysis The conclusion is that Urokinase Vena thrombolysis treat Senile AMI is safe and effective,if strictly choosing case and preventing complication such as bleeding