糖尿病患者第3腰椎骨密度测量的意义

SIGNIFICANCE OF MEASURING BONE MINERAL DENSITY OF THE THIRD LUMBAR VERTEBRAE IN DIABETIC PATIENTS

糖尿病（ＤＭ）患者继发骨质疏松较多见，为探讨早期诊断，对３０例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者和４０例正常对照者，进行血清钙（Ｃａ）、磷（Ｐ）、碱性磷酸酶（ＡＫＰ）的测定，拍照胸部、腰椎和骨盆Ｘ线片，并分别经ＣＴ进行第３腰椎骨密度（ＢＭＤ）测量。结果，ＤＭ组ＢＭＤ均值为１２７．１±２５．７７ｍｇ／ｃｍ３，对照组ＢＭＤ均值为１８９．１１±７１．６８ｍｇ／ｃｍ３，两组比较有非常显著差异（Ｐ＜０．０１），提示第３腰椎骨密度测量对ＤＭ患者骨质疏松的早期诊断有一定价值。

It is more frequent that diabetic patients have secondary osteoporosis.In order to probe into the early diagnosis,serum Calcium,serum phosphorus and serum AKP were assayed in 30 NIDDM patients (group Ⅰ) and 40 normal controls (group Ⅱ);X ray films of the chest,vertebra and pelvis were examined and bone mineral density (BMD)of the third lumbar vertebrae was measured by CT in the two groups.The results were as follows:the average BMD in diabetic patients was 127.1±25.77mg/cm 3,and in normal controls was 189.11±71.68mg/cm3;there were significant differences between the two groups in BMD (P〈0.01).These results suggest that measuring bone mineral density of the third lumbar vertebra has predicative value for the early diagnosis of diabetic osteoporosis.