母体二十二碳六烯酸摄入水平与婴儿智能发育的关系

Study on the relationship between maternal intake of docosahexaenoic acid and the mental development of infant

目的:探讨母体二十二碳六烯酸(DHA)摄入水平与婴儿智能发育的关系。方法:将孕妇分为A组(DHA平均摄入量<80mg/d)、B组(DHA平均摄入量80～159mg/d)、C组(DHA平均摄入量≥160mg/d)各20例,用毛细管气相色谱法测定3组孕妇于妊娠(20±2)周、(32±2)周、生后4周及足月时的静脉血及其新生儿脐血血清的DHA水平,对其婴儿于出生后3～4个月采用中国儿童发展中心(CDCC)制定的0～3岁婴幼儿智能发育量表进行评价,得出精神和运动发育指数(MDI和PDI)。结果:C组血清DHA含量高于B、A组,差异非常显著(P<0.01),C组MDI、PDI显著高于B、A组(P<0.01)。结论:母体二十二碳六烯酸(DHA)的摄入水平与婴儿智能发育有密切关系。

Objective：To investigate the relationship between maternal intake of docosahexaenoic acid（DHA）and the mental development of infant.Methods：Pregnant women were assigned into three groups：20 cases in group A（the average intake of DHA〈80 mg/d）,20 cases in group B（the average intake of DHA 80 mg/d-159 mg/d）and 20 cases in group C（the average intake of DHA≥160 mg/d）.DHA levels were measured from the serum of pregnant women during（20±2）weeks,（32±2）weeks and full-term gestation,as well as from serum of neonatal cord blood,maternal after 4 weeks postpartum by capillary gas chromatography and mental development evaluation according to Children＇s Development Center of China（CDCC）were carried out in babies of 3-4 months old to obtain the mental development index（MDI）and psycho-motor development index（PDI）.Results：DHA levels were significant higher in group C than that in group B and A（P〈0.01）.MDI and PDI of group C were significantly higher than that of group B and A（P〈0.01）.Conclusion：The maternal intakes level of DHA are closely related to the intellectual development of infants.