摘要
本文以室颤阈(VFT)为指标,观察了家兔心肌缺血40min和再灌注40min过程中VFT的变化及SOD和654-2对其变化的影响。缺血心肌再灌注早期,VFT呈现一过性降低;再灌注前给予SOD或654-2,均可减轻VFT降低的程度,二者联合用药,有较好的协同效应。
The dynamic changes of VFT were observed during the period of 40min ischemia and the following 40min of reperfusion. The results indicated:①VFT reduced transiently during the early period of reperfusion; ②administration of SOD or 654—2 before reperfusion alleviated the degree of VFT reduction, and the combination of SOD and 654—2 eliminated the decrease in VET completely.
关键词
心肌缺血
再灌注
室颤阈
SOD
myocardial ischemia
reperfusion
ventricular fibrillation threshold
superoxide dismutase
654—2
