踝臂指数与缺血性脑血管病颅内动脉狭窄的关系

Relationship between Ankle-brachial Index and Intraca Artery Stenosis in Patients with Ischemic Cerebrovascular Disease

目的探讨踝臂指数(ABI)与缺血性脑血管病颅内动脉狭窄的关系。方法收集100例缺血性脑血管病患者,根据经颅多普勒(TCD)、磁共振血管造影(MRA)结果分为无狭窄组与狭窄组(包括单支狭窄组、二支狭窄组和三支以上狭窄组)。所有入选对象均进行ABI测量。结果狭窄组ABI异常率显著高于无狭窄组(P<0.05);狭窄组的ABI值(0.88±0.16)显著低于无狭窄组(1.04±0.07)(P<0.05)。无狭窄组与单支狭窄组、二支狭窄组和三支以上狭窄组两两比较ABI异常率有显著性差异(P<0.05),无狭窄组ABI异常率低于各狭窄组;三支以上狭窄组ABI值(0.79±0.17)显著低于单支狭窄组(0.93±0.12)和二支狭窄组(0.92±0.15)(P<0.05),但单支狭窄组与二支狭窄组之间差异无统计学意义(P>0.05)。结论ABI与颅内动脉狭窄数量有关。

Objective To explore the relationship ankle-braehial index （ABI） and intraeal artery stenosis in patients with isehemie eerebrovaseular disease. Methods One hundred patients with isehemie eerebrovaseular disease were enrolled in this study. Patients were divided into two groups according to transeranial doppler （TCD） and magnetic resonance angiogram（MRA） and there were non-stenosis group and stenosis group （including to 1-vessel stenosis group,2-vessel stenosis group,3-vessel stenosis group ） in this study. All the objects underwent ABI. Results The ratio of ABI abnormality was different between patients with intraeal artery stenosis and patients without intraeal artery stenosis（P〈0.05）. The value of ABI （0.88±0.16）in patients with intraeal artery stenosis was lower than patients without intraeal artery stenosis（1.04±0.07） （P〈 0.05）. Compared with non-intraeal artery stenosis group, the ratio of ABI abnormality in 1-vessel stenosis group, 2-vessel stenosis group and 3-vessel stenosis group were significantly different （P〈0.05）. The value of ABI in 3-vessel stenosis group（0. 79±0. 17） was significantly lower than those in 1-vessel stenosis group（0.93±0.12） and 2-vessel stenosis group（0.92±0.15）（P〈 0.05）. But the value of ABI was not significantly different between 1-vessel stenosis group and 2- vessel stenosis group（P〉0. 05）. Conclusion ABI is associated with the quantity of intraeal artery stenosis.