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丝/苏氨酸激酶Pim家族研究相关进展 被引量:3

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作者 简捷 黄缘
出处 《实用临床医学(江西)》 CAS 2008年第6期129-130,共2页 Practical Clinical Medicine
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  • 1Aho T L, Sandholm J, Peltola K J, et al. Pim-1 Kinase Promotes Inactivation of the Pro-apoptotic Bad Protein by Phosphorylating It on the Set112 Gatekeeper Site[J]. Febs Lett, 2004,57:43-49.
  • 2Wang Z, Bhattacharya N, Meyer M K, et al. Pim-1 Negatively Regulates the Activity of PTP-U2S Phosphatase and Influences Terminal Differentiation and Apoptosis of Monoblastoid Leukemia Cell[J]. Arch Biochem Biophys,2001,390(1) :9-18.
  • 3Lilly M,Sandholm J ,Cooper J J ,et al. The Pim-1 Serine Kinase Prolongs Survival and Inhibits Apoptosis-related Mitochondrial Dysfunction in Part Through a Bcl-2-dependent Pathway[J]. Oncogene ,1999 , 18(27): 4022-4031.
  • 4Bachmann M, Hennemann H, Xing P X, et al. The Oncogenic Serine/threonlne Kinase Pim-1 Phosphorylates and Inhibits the Activity of Cdc25C-associated kinase 1 (C-TAK1) [J]. J Biol Chem,2004,279(46) :48319-48328.
  • 5Bachmann M, Moroy T. The Serine/threonine Kinase Pim-1[J].Int J Biochem Cell Biol,2005,37(4) :726-730.
  • 6Kim K T, Levis M, Small D. Constitutively Activated FLT3 Phophorylates BAD Partially Through Pim-1[J]. Br J Haematol,2006,13(5):500-509.
  • 7Holder S, Zemskova M, Zhang C, et al. Characterization of a Potent and Selective Small-molecule Inhibition of the Pim-1 Kinase[J]. Mol Cancer Ther,2007,6(1):163-172.
  • 8Xu Y,Zhang T,Tang H,et al. Overexpression of Pim-1 is a Potential Biomarker in Prostate Carcinoma[J].J Surg Oncol, 2005,92(4): 326-330.
  • 9Chiang W F, Yen C Y, Lin C N, et al. Up-regulation of A Serine-theronine Kinase Pro-oncogene Pim-1 in Oral Squamous Cell Carcinoma[J]. Int J Oral Marillofac Surg, 2006,35 (8): 740-745.
  • 10Beier U H, Weise J B, Laudien M, et al. Overexpression of Pim-1 in Head and Neck Squamous Cell Carcinomas[J]. Int J Oncol, 2007,30(6) : 1381-1387.

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