婴幼儿肺炎血清心肌酶谱活性变化与病情关系

ASSOCIATION OF STATE OF ILLNESS AND MYOCARDIAL ENZYMOGRAM ACTIVITY FOR INFANT PNEUMONIA

目的：探讨婴幼儿肺炎血清心肌酶谱变化与病情的关系。方法：选择有并发症婴幼儿肺炎２５例（重症组）、无并发症肺炎３２例（轻症组）和无肺、心、脑疾病２０例（对照组），采用酶动力学速率法检测各组急性期与恢复期血清心肌酶谱活性，并相互比较。结果：轻、重症组急性期心肌酶谱活性升高，与对照组比较有显著差异（Ｐ＜００５，Ｐ＜００１），且轻、重症两组比较有显著性差异（Ｐ＜００５，Ｐ＜００１）；恢复期心肌酶谱活性下降正常，各组间无显著性差异（Ｐ＞００５）。结论：婴幼儿肺炎心肌酶谱活性与病情密切相关，监测心肌酶谱变化对估价病情、指导治疗有重要意义。

OBJECTIVE: To determine association of state of illness and myocardial enzymogram activity for infant pneumonia. METHOD: 25 cases of pneumonia with complications (severe symptom group) and 32 cases of pneumonia without complication (mild symptom group) as well as 20 hospitalized patients without lung、 heart and brain problem (control group) were selected. The activity of mgocardial enzymogram during convalescence and acute stage for each group was detected and the results were compared. RESULTS: The activity of myocardial enzymogram in mild and severe symptom group during acute stage increased and was significantly higher than control group (P<005, P<001 respectively). Also, The difference was significant between mild and severe symptom group (P<005, P<001). During convalescence, the activity of enzymogram decreased and had no significant difference among the groups (P>005). CONCLUSION: The activity of cardial enzymogram is closely associated to state of illness. Monitoring of enzymogram is valuable in assessing disease progress and directing therapy.