乳腺癌患者综合治疗后肺部早期放射性反应

Early radiation response of the lung in breast cancer patients treated with comprehensive therapy

作者总结了经过手术、放疗和化疗等综合治疗的６２例乳腺癌病例。化疗用ＣＭＦ或ＣＡＭＦ方案。肺部早期放射性反应的发生率为１１．３％（７例），而且早期肺放射性反应发生率均发生于含阿霉素的ＣＡＭＦ化疗方案病例中，说明阿霉素与放射治疗合并使用会增加早期肺放射性反应的发生率。因此，综合治疗中，为了既得到好的治疗效果又减少肺部早期放射性反应的发生，对于用阿霉素化疗的病例，我们应该适当控制总照射剂量，精确设计放射野。

62 breast cancer patients were treated with comprehensive therapy between June 1992and January 1995. Comprehensive therapy includes surgery,radiotherapy and chemotherapy with CMF(CTX,MTX,5-FU) or CAMF (CMF plus ADM) regimen. Incildehce of early radiation resPOnse of thelung was 11. 3% (7 patients). All the cases were in the group of CAMF regimen. It shows that adriamycin can increase the incidence of early radiation response of the lung. To acquire good result and reduce the incidence of early radiation response of the lung,for the patients treated with CAMF regimen,we should control the total radiation dose properly and design the radiation fields precisely.