摘要
观察去氧胆酸钠复制的急性出血坏死性胰腺炎（Ａｃｕｔｅｈａｅｍｏｒｈａｇｉｃａｎｄｎｅｃｒｏｔｉｓｉｎｇｐａｎ－ｃｒｅａｔｉｔｅｓＡＨＮＰ）大鼠血浆ＮＯ的变化以及中药大黄、丹参对其影响。结果表明，ＡＨＮＰ过程中ＮＯ的产生明显增加，并随进程呈上升趋势，丹参对此有抑制作用。大黄对ＡＨＮＰ时的ＮＯ产生则显示出先促进后抑制的双向作用。
he study observed the changes of plasma NO concentrations and the effects of administration of Chinese medicine (Radix Rheum officinale and Radix Salvia miltiorrhizae solution) on the changes above in the rats with acute haemorrhagic and necrotising pancreatitis (AHNP) induced by intra pancreaticduct injection of deoxycholic acid Na.The result show that the plasma NO concentrations significantly increase after operation and display uptrend with the progress of AHNP.Administration by oral of the Radix Salvia miltiorrhizae solution can inhibit the increase of plasma NO,but Radix Rheum officinale solution can promote at the beginning (12 h after AHNP) and depress at the later (24 h after AHNP) the produce of NO significantly in AHNP rats.
出处
《贵阳医学院学报》
CAS
1997年第3期231-233,共3页
Journal of Guiyang Medical College
基金
贵州省教委资助
