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蚯蚓与固有免疫

Earthworm and innate immunity
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摘要 动物的免疫系统包括固有免疫和适应性免疫。固有免疫是指动物机体与生具有的抵御微生物或者外来异物侵袭的能力,包括组织屏障作用、细胞免疫作用和体液免疫作用。固有免疫细胞识别病原体表面的模式分子而活化,经特殊信号转导途径产生免疫效应。蚯蚓属无脊椎动物,其免疫系统缺乏免疫球蛋白,适应性免疫不发达,主要依赖固有免疫机制来抵御微生物的感染。 Zoic immune system including innate immunity and adaptive immunity. Innate immune system is a general defense mechanism which is built up in the process of development and evolution of biological species, including tissue barrier function, cell-mediated immunity, and humor immunity. Innate immunocytes are activated by the recognition of mode elements on the pathogen. The immunological effect is produced through special signal transduction pathway. Earthworm belongs to invertebrate whose immune system lacks immunoglobulin and has not developed adaptive immunity. So earthworm protects itself through innate immunity.
作者 刘志贞 牛勃
出处 《国际免疫学杂志》 CAS 2008年第4期253-256,共4页 International Journal of Immunology
基金 国家自然科学基金资助项目(30472251)
关键词 蚯蚓 固有免疫 核酸酶 Earthworm Innate immunity Nuclease
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