婴幼儿肺炎链球菌肺炎患儿潮气呼吸肺功能的改变

Changes of Tidal Pulmonary Function in Infants of Streptococcus Pneumoniae Pneumonia

目的探讨肺炎链球菌(SP)肺炎患儿肺功能的变化。方法应用V26max肺功能仪测定35例0￣3岁SP肺炎患儿的潮气呼吸流速容量环和肺功能各项指标,以36名同龄健康体检儿童作对照,并和37例同龄呼吸道合胞病毒(RSV)肺炎患儿作对比。结果SP肺炎组患儿与正常对照组相比,呼吸频率(RR)增快,呼气峰流速/呼气达峰时间(PTEF/tPTEF)升高,每公斤潮气量(VT/kg)、达峰时间比(tPTEF/tE)、剩余25%潮气量时的呼气流速(TEF25%)、达峰容积比(%V-PF)、剩余25%潮气量时的呼气流速/呼气峰流速(25/PF)、平均呼气流速(MEF)、平均吸气流速(MIF)下降,差异均有统计学意义(均P<0.05)。SP肺炎组与RSV肺炎组相比,RR增快,MEF、MIF及TEF25%下降,差异均有统计学意义(均P<0.05)。结论SP肺炎患儿大小气道均有损害,通气功能障碍,肺功能下降,且较RSV肺炎患儿为重。使用V26max肺功能仪来测定潮气呼吸流速容量环和肺功能各项指标,可用来判断患儿支气管肺炎的严重程度,并为各种病原感染提供诊断及治疗帮助。

Objective To explore the changes of tidal pulmonary function in paediatric patients of streptococcus pneumoniae pneumonia. Methods In 35 patients the lung function parameters were measured and recorded by V26max pulmonary function testing （PFT） machine.Campared with agematched 36 healthy children and 37 patients suffering from respiratory syncytial virus （RSV）pneumonia. Results Compared with hea/thy children,in pediatric patients with streptococcus pneumoniae pneumonia RR and PTEF/tPTEF increased while VT/kg、TFFEF/TE、TEF25%、%V-PF、 25/PF、 MIF and MEF significantly decreased compared with the healthy individuals （P〈0.05）.Some parameters in patients with streptococcus pneumoniae such as MEF、MIF and TEF25% were lower than those in patients RSV pneumonia, in patients with streptococcus RR increased compared with patients with RSV pneumoniae（P〈0.05）. Conclusion The ventilate function of patients with strep- tococcus pneumoniae is injured,both big and small airway are obstructed. The machine can be used to evaluate the grade of disease and guide clinical treatment.