钛镍记忆合金网状支架治疗食管贲门狭窄

Treatment of esophageal and cardiac stricture with TiNi memory alloys srent

作者使用形状记忆合金支架治疗９５例食管恶性狭窄，３５例吻合口瘢痕狭窄。所有病例均失去手术机会，使用扩张、化疗、放疗、激光等治疗也无效。治疗后，吞咽困难从３．７１±０．４５（３～４级）降到１．０８±０．５９（０～２级）（Ｐ＜０．０１）。并发症发生４９例（３１．５％），其中胸痛３６例，出血５例，肿瘤过度生长４例，支架移位２例，食物堵塞２例。通过近三年的临床应用和疗效观察，作者认为，食管贲门狭窄放置钛镍记忆合金支架是一种有效、安全、简单方法。

A thermal shaped menory metal stent, which is made of Nitinal, used in 95 patients with malignant tumors and 35 patients with anastomosis stenosis tumor resection. All patients had no opportunities of surgical operation and no reponse to dilation radiotherapy,chemotherapy,lasertherapy and traditional Chinese medicine.Dysphagia ameliorated in all patients after stent therapy.The mean dysphagia grade varied from 3 71±0 45(range 3￣4) to 1 08±0 59(range 0￣2)( P <0 01). Complications occurred in 49 patients (31 5%),including chest pain in 36 ,local bleeding in 5,tumor overgowth in 4, stent migration in 2, and food obstraction in 2 In summary,treatment with placement of a Nitinol stent is effective, safe and simple in our patients with dysphagia which were due to malignant esophageal and cardiac strictures and is feasible for some benign esophageal and cardiac strictures as well through our clinical practice and observtion nearly three years.