阻塞性睡眠呼吸暂停综合症患者血氧饱和度下降程度与其它有关指标的相关性研究

Relationship between Decreased Saturation of Blood Oxygen Level and Other Related Data in Patient with Obstructive Sleep Apnea Syndrome

目的：探讨阻塞性睡眠呼吸暂停综合症（OSAS）患者血氧饱和度下降程度与其它有关指标的相关性。方法：57例睡眠初筛检查诊断为OSAS患者的数据中选取呼吸暂停低通气指数（AHI）、体重指数（BMI）、鼾声指数、呼吸暂停低通气累积时间、血氧饱和度在80%～89%区间的累积时间、血氧饱和度≤79%的累积时间按血氧饱和度85%～89%、80%～84%、≤79%排序分为3组,进行统计学处理;并将血氧饱和度下降程度与上述各测定指标的关系进行相关性分析。结果：3组间比较仅年龄和BMI差异无显著性意义,其余指标均差异有显著性意义（P〈0.05）;相关分析显示,除BMI和鼾声指数与血氧饱和度下降程度无明显相关性外,其余指标与血氧饱和度下降程度呈明显负相关关系。结论：OSAS患者是否出现缺氧及缺氧的严重程度与BMI和鼾声指数并无必然的联系;OSAS患者BMI均值皆达到超重或肥胖程度,且缺氧程度的增加与AHI均值的增高相一致,说明减肥和降低体重是OSAS康复干预的一项重要措施;在给OSAS患者康复干预建议时,缺氧累积时间应列为全盘考虑中。

Objective：To study the relativity between the decreased saturation of blood oxygen level and other related data in patients with obstructive sleep apnea syndrome （OSAS）. Methods： Fifty-seven patients diagnosed as having OSAS were divided into 3 groups according to the saturation of blood oxygen： （85- 89） %, （80 - 84） % and ≤ 79 %. AHI,BMI,snore index,apnea-hypopnea accumulation time,acumination time between （80--90）% and ≤79% were compared. The SPSS 12.0 statistic tool was used to run a t-test on the data. The SPSS 12.0 statistic tool was also used to analyze the relationship between the decreased saturation of blood oxygen level and the above data. Results： There was no significant difference in age and BMI among groups, but there was significant difference in other data （P〈0.05）. Relative analysis showed that BMI and snore index had no clear relevance to the decreased saturation of blood oxygen level. But AHI,apnea hypopnea accumulation time, accumulation time for the saturation of blood oxygen between （80- 90）% and ≤79% had a clear negative relation with the decreased saturation of blood oxygen level. Conclusion：Whether patients with OSAS have anoxia and anoxia degree has no necessary relation with BMI and snore index. However,this study shows that despite the anoxia degree, the average BMI of patients with OSAS has reached the overweight or obesity level. The AHI increase is in line with the anoxia degree increase,which indicates losing weight is still an important treatment for pa tients with OSAS. Anoxia accumulation time used to be ignored. But we suggest that we should take it into consideration in the rehabilitative treatment of patients with OSAS.