芪丹通脉片对运动训练大鼠力竭时间的影响

Effects of Qidantongmai supplement on exhaustive time during exhaustive exercise in rats

目的:通过观察芪丹通脉片对参与运动训练大鼠力竭时间的影响,探讨活血化淤类药物对机体力竭时间的影响及其作用机制。方法:10周龄雄性SD大鼠16只随机分为2组:单纯运动训练组及芪丹通脉片+运动训练组。芪丹通脉片+运动训练组灌服芪丹通脉片生理盐水溶液(3.24mg/kg),而单纯运动训练组给予灌服相同体积的生理盐水。实验期间两组大鼠先进行2周适应性游泳训练,然后进行4周递增负荷游泳训练并于第4周末进行力竭运动实验并计算力竭时间。结果:芪丹通脉片+运动训练组的力竭时间显著高于单纯运动训练组。结论:6周灌注芪丹通脉片后可以改善大鼠疲劳训练的机能状态,延长力竭运动中的力竭时间。

Objectlve：To observe the effects of QDTMT Supplement on exhaustive time during exhaustive exercise in ratss.Method：Sixteen 10- week old male SD rats were divided into two groups at random： movement training group and QDTMT＋movement training groups. Rats in QDTMT＋movement training groups were effused QDTMT（3.24mg/ Kg）orally, whereas rats in control group were effused saline solution in the same volume respectively. After all rats finished 2 weeks of adaptation swimming training, the rats were taken 4 weeks of increment load swimming training. In the last day of the 4th week, the rats were forced to take a swimming exercise until exhaustive.Result： In the QDTMT＋ movement training group, the exhaustive time was increased significantly compared with the movement training groups.Conclusion：QDTMT supplement can improve rats＇conditioning during exhaustive exercise, and increase the exhaustive time.