胃肠道间质瘤的螺旋CT诊断及临床应用

Spiral CT diagnosis of gastrointestinal stromal tumors

目的分析胃肠道间质瘤（GIST）的螺旋CT表现及其在临床治疗方面的应用价值。方法对32例经手术病理证实的GIST患者的螺旋CT影像资料及临床资料进行回顾性分析。结果本组GIST中位于食管1例，胃22例，结肠系膜1例，小肠6例及结肠2例；良性4例，恶性28例；免疫组化染色CD117阳性表达率为75％，CD34阳性表达率为81％；病变多为外生型56％，良性病灶最大径平均为4．75cm，而恶性病变最大径平均为6．78cm。结论螺旋CT能够为GIST的定位、定性诊断提供重要的参考依据，但对GIST的定性诊断仍需要免疫病理来确定。

Objective To evaluate spiral CT diagnosis of gastrointestinal stromal tumors （GIST）. Methods The CT findings and clinicopathological data of 32 GIST cases were retrospectively analyzed. Results Of the 32 GIST cases, 1 located in the esophagus, 22 in the stomach, 1 in the mesentery, 6 in the small intestine and 2 in the colon. There were 4 benign and 28 malignant cases. Expression of CD117 and CD34 was 75% and 81% respectively. The lesions were exogenous in 56% cases. The average size of the benign and malignant masses was 4.75 cm and 6.78 cm respectively. Conclusions Spiral CT could provide important information for the diagnosis and localization of GIST, but the final diagnosis still relies on oathology.