摘要
游离循环DNA是一种细胞外游离状态的DNA,在动植物及人的体液中都检测到了它的存在。对游离循环DNA的检测已经应用在疾病的监控、胎儿的产前诊断及肿瘤的研究中。文章介绍了循环DNA的生物学特征,并对近年来游离循环DNA的研究和应用进展做了简单的回顾。
Free circulating DNA is one kind of extracellular free DNA, which was examined in the zoology, botany and the human's body fluid. The detection of free circulating DNA had already been applied in monitoring the disease, embryo's pre-natal diagnosis, tumor research. This article reviewed some biology characteristics of free circulating DNA, the recent researches of free circulating DNA and its application.
出处
《遗传》
CAS
CSCD
北大核心
2008年第7期815-820,共6页
Hereditas(Beijing)
基金
南开大学技术创新专项基金项目(编号:06-h83)~~
关键词
游离循环DNA
疾病诊断
肿瘤
产前诊断
free circulating DNA
the diagnosis of disease
tumor
prenatal diagnosis