摘要
目的探讨2型糖尿病男性患者性激素水平与冠心病发病之间的关系。方法2型糖尿病男性患者102例,分为冠心病合并组(n=58)和无冠心病合并组(n=44),测定两组血清睾酮、性激素结合球蛋白、血压、血脂及血糖,计算体质指数。结果冠心病合并组血清睾酮和性激素结合球蛋白水平与无冠心病合并组相比明显降低,两组血压、血脂和体质指数差异有显著性(P<0.05),但血糖差异无显著性。结论合并冠心病的2型糖尿病患者男性激素水平比无冠心病合并患者明显降低,认为男性糖尿病患者男性激素水平降低是发生冠心病的重要危险因素。
Aim To investigate the relationship between sex hormone levels and coronary heart disease （CHD） in diabetic men. Methods The serum testosterone （T） and sex hormone binding globulin （SHBG）, lipids, glucouse were as-sayed. Blood pressure, body mass index （BMI） were studied in 102 cases of diabetic men, inclnding 58 cases with CHD, and 44 cases without CHD （NCHD）. Results Serum levels T and SHBG were decreased significantly, the differences of BP, lipids, BMI remained statistically significant, but serum glucose had no statistically significant difference in CHD compared with fast NCHD. Conclusion Diabetic men with CHD have significant lower levels of T and SHBG than without CHD. Lower levels of sex hormone is an important risk factor of CHD in diabetic men.
出处
《中国动脉硬化杂志》
CAS
CSCD
2008年第5期395-396,共2页
Chinese Journal of Arteriosclerosis
关键词
内科学
糖尿病
冠心病
睾酮
性激素结合球蛋白
Diabetic Mellimn
Coronary Heart Disease
Testosterone
Sex Hormone Binding Globulin
