摘要
①目的探讨血卟啉衍生物（ＨＰＤ）对恶性肿瘤放射治疗的增敏作用。②方法应用图象分析技术测定大鼠移植Ｗ２５６肿瘤单纯放射治疗组（对照组）和ＨＰＤ并放射治疗组（实验组）肿瘤细胞的ＤＮＡ含量。③结果实验组大鼠肿瘤细胞ＤＮＡ含量为５．８４±１．２２Ｃ；对照组大鼠肿瘤细胞ＤＮＡ含量为７．８３±０．６８Ｃ；两组比较差异有极显著性（ｔ＝６．３７，Ｐ＜０．０１）。④结论ＨＰＤ对放射治疗恶性肿瘤有明显的增敏作用。
Objective To study the sensitizing effect of hemotoporphyrin derivation(HPD) on radiotherapy for transplanted tumor in mice. Methods DNA contents of W 256 tumor cells in both radiotherapy group(control group) and radiotherapy plus HPD group(experimental group) were measured with image analysis technique. Results DNA content of tumor cells was 5.84±1.22C in the experiment group and 7.83±0.68C in the control group. Conclusion PHD has significantly sensitizing effect on radiotherapy for malignant tumors.
出处
《青岛医学院学报》
1997年第2期127-128,共2页
Acta Academiae Medicinae Qingdao Universitatis
基金
山东省科委基金
