微波与洗必泰协同杀菌效果的试验观察

EXPERIMENTAL OBSERVATION ON SYNERGETIC GERMICIDAL ACTION OF MICROWAVE AND CHLORHEXIDINE

试验表明，６５０Ｗ微波与０．５％洗必泰溶液协同作用５分钟，可使在聚丙烯塑料密封包装内的物品达到灭菌。医院内应用试验，检测３９８份医疗器械，全部达到灭菌。此法累积作用７２小时，对碳钢和铝有轻度腐蚀，对不锈钢与黄铜基本无腐蚀。

Experimental observation on synergetic germicidal action of 650 W microwave and chlorhexidine solution was carried out. Stainless steel discs were artificially contaminated with Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Bacillus subtilis var. niger spore, Bacillus stearothermophilus spore and HBsAg and put in the center of dressing pack wrapped by polyacrylate or in a glass vial (10 ml) containing chlorhexidine solution, which was put in a plastic box (loading with 400 ml distilled water). The dressing pack and the plastic box were then exposed to microwave radiation. The results showed that after exposure to synergetic action of 650 W microwave and 0.5% chlorhexidine solution for 5 min, the stainless steel discs in the dressing pack containing 75% water (proportion of weight) within the polyacrylate wrap or in the chlorhexidine solution of the glass vial within the plastic box were sterilized. 398 medical instruments in 4 hospitals were treated with such method and all were found to be sterilized. Treatment with this method for 5 min each time caused slight corrosion of carbon steel and aluminum after a cumulative exposure time of 72 hr, while essentially no corrosion occurred in stainless steel and copper.