主动脉内囊反搏和天麻注射液联合使用对山羊心肌缺血──再灌注损伤的改善作用

The Effect of Combining Intra-Aortic Balloon Pumping with Tianma Injection on Myocardial Ischemic-Reperfusional Injury in Goats

采用结扎2h继而开放山羊冠状动脉分支方法，复制心肌缺血──再灌注模型，观察主动脉内囊反搏和天麻注射液联合使用对心肌坏死区面积的影响。所得结果与二者单独使用的结果进行了比较，发现主动脉内囊反搏和天麻注射液联合使用对限制心肌坏死区大小具有明显的协同作用。

The objective of this study was to explore the effect of combined Intra-Aortic Balloon Pumping (IABP) and Tianma injection on necrotic area in goat myocardial ischemic-reperfusional models which were established by two hours ischemia and a follow-up reperfusion. The results showed that the combined effect of IABPand Tianma Injection was more significant than that of IABP or Tianma separately. It is suggested that IABP andTianma injection have synergetic effect on the limitation of necrotic area, which possibly results from their mechanisms for decreasing the size of infarct.