心肌收缩蛋白的结构与功能研究进展

The Advances of Research for Cardiac Contractile Proteins Structure and Function

心肌收缩蛋白是心肌产生收缩的物质基础。本文介绍了两种主要心肌收缩蛋白：肌凝蛋白（myosin）和肌动蛋白（actin）的结构，尤为详细地讨论了与其功能相关的部分，并就正常与异常心脏中两者的改变作一阐述，以期深化心肌肥大和心力衰竭分子水平上的变化认识。

Cardiac contractile proteins are the material basis of cardiac contractility. This paper introduces theStructures of two major cardiac contractile proteins: myosin and actin, especially the details of the two proteins'structure relevant to their function. At the same time, it describes the myosin and actin proteins' changes in normal and abnormal hearts so as to enrich our mind with knowlege of cardiac hypertrophy and heart failure at themolecular level.