摘要
综合报道国内16所医院分娩的初产妇1828例,随机分为两组,分别给予米索前列醇和催产素进行足月妊娠引产的病例对照研究。结果:米索前列醇用于足月妊娠的有效率为93.56%,显著高于催产素组79.49%(P<0.01),其临产发动时间及总产程分别为(2.95±0.53)h和(6.35±2.21)h,短于催产素组的(3.75±0.61)h及(9.09±2.41)h(P<0.01);剖宫产率为8.89%亦显著低于催产素组17.05%(P<0.01);两组新生儿体重及新生儿窒息发生率均无显著差异(P>0.05)。因此认为:米索前列醇用于足月妊娠引产能缩短产程,降低剖宫产率,有利于计划分娩,是一种安全有效的引产方法。
Objective: To observe the efficacy of misoprostol in induction of term labor.Design: Uniparous parturients (n=1,828) in 15 hospitals were randomized into two groups. The study group was given misoprostol, and the control group was administered oxytocin. Results: Success rate of misoprostol in induction of labor was 93 56%, significantly higher than that of oxytocin (79.49%) ( P< 0. 01) . The interval between administration of drugs and onset of labor and the duration of labor were 2. 95 ±0. 53 hours and 3. 75 ±0. 61 hours, respectively,for the study group, significantly shorter than those for the control group (6.35±2.21 and 9.09±2.41 hours, respectively, P< 0 01). In addition, Cesarean section rate in the study group was 8. 89%, significantly lower than that in the control group (17.05%, P< 0. 01) . Mean birth weight and the incidence of neonatal asphyxia in the two groups were similar (P>0.05). Conclusion: Application of misoprostol in induction of term labor can effectively shorten the course of labor, lower Cesarean section rate, and may be useful for planned delivery. \ \
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1997年第5期287-288,共2页
Chinese Journal of Practical Gynecology and Obstetrics