异基因造血干细胞移植术层流室规范化护理(附89例护理体会)

目的探讨规范化护理对造血干细胞移植疗效的影响并总结临床护理经验。方法回顾性调查血液科移植组89例异体造血干细胞移植术患者的并发症、住仓天数及成功率。结果移植成功率79%(70/89),失败21%(19/89),患者住层流室时间均值35±6d。并发症45%(40/89)。ABO血型不符合11例,无1例发生溶血反应。结论恰当正常的规范化护理,能有效减少移植后并发症,有利于患者度过骨髓移植难关,顺利出仓。

To evaluate the effects of a Standardized Nursing Intervention Protocol on overall outcomes of patients undergoing allogeneic hematopoietic stem cell transplantation （AHSCT）, and to summary the nursing experience. Methods： Post-transplant complications, length of stay in the laminar-airflow unit, and the transplant success rates were investigated by a retrospective study on 89 patients received AHSCT in our department between Jan. 2002 and Dec. 2007. Results： Post-transplant complications were noted in 40 out of 89 cases （45%）. The average stay in the laminar-airflow unit was 35±6 days. The success rates were 79 % （70/89）, while the failure rates 21% （19/89）. Among these cases, 78 were donor-recipient ABO-identical, 11 were ABO-incompatible, No hematolysis occurred even in the condition of ABO-incompatibility. Conclusions： A proper Standardized Nursing Intervention Protocol is likely to be of benefit in preventing the complications, and to offer a greater chance of transplant SUCCESS.