摘要
检测65例脑出血外周血皮质醇、T淋巴细胞亚群的变化,结果发现,脑出血皮质醇明显升高,T淋巴细胞亚群中CD+3、CD+4、CD+4/CD+8降低,CD+8升高,提示脑出血下丘脑垂体肾上腺皮质功能活跃,细胞免疫功能下降。同时发现皮质醇增高程度、细胞免疫功能下降程度与脑出血预后密切相关,可作为判定病情程度及预后的重要参考指标。
This study measured the change of cortisol and T lymphocyte subsets in 65 cases of cerebral hemorrhage. The results showed that the level of cortisol increased abviously and CD + 3,CD + 4 and CD + 4/CD + 8 decreased, CD + 8 increased. The activity of hypothalamus pituitury adrenocortical system increased and the function of cellular immunity lowered. The changes of cortisol and T lymphocyte subsets and closely related to prognosis of cerebral hemorrhage and may be used as an important parameter for clinical and prognostic evalution.
关键词
脑出血
预后
T细胞亚群
皮质醇
MeSH cerebral hemorrhage
T lymphocytes/CL
adrenal cortex hormones
prognosis