婴儿肠绞痛3种疗法的临床观察

Observation of three therapies for infant colic

目的比治疗婴儿肠绞痛(infant colic)3种方法的临床效果。方法将112例肠绞痛患儿分为3组,分别采用行为非药物疗法、氯苯那敏,西甲硅油乳剂治疗。结果3组患儿在治疗后症状都有明显改善,用药3d后,西甲硅油组最为明显,痊愈和改善者占90%(36/40),氯苯那敏组次之,痊愈或改善者占75%(30/40),非药物组改善者占43.75%(14/32),西甲硅油组治疗3d后哭闹时间缩短63.52%,氯苯那敏组缩短50.30%,非药物治疗组缩短16.55%。3组间哭闹和激惹时间的缩短有显著性差异(P﹤0.01)。结论西甲硅油和氯苯那敏对婴儿肠绞痛有明确的疗效,可结合非药物疗法治疗婴儿肠绞痛。

Objective To investigate the effect of three therapies for infant colic. Methods 112 infants with colic were divided into three groups. Group 1 received dietary and behavioral therapy. Group 2 received chlorpheniramine and Group 3 received simethicone. Results Three therapies were all effective. Simethicone was the best one, followed by chlorpheniramine. In simethicone group, the infants＇ crying time decreasing by 63.52%, in chlorpheniramine group decreasing by 50.33% and in dietary therapy group decreased 16.55%. The decreased time of crying was signigicantly different among the three groups. Conclusions Simethicone and chlorpheniramine are effective for infant colic and can be combined with non-drug therapy.