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关节镜下自体骨软骨移植修复软骨缺损 被引量：2

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摘要 目的总结关节镜下自体骨软骨镶嵌移植术(osteochondral autologous transplantation,OAT)修复膝关节软骨缺损的方法及临床效果。方法2000年8月-2005年6月,采用关节镜下OAT治疗23例股骨髁关节软骨缺损。男15例,女8例;年龄16～41岁。运动冲撞伤13例,跌伤2例,8例无明显诱因或外伤史。病程1～8个月。软骨缺损深度按照国际软骨修复协会标准分级:4级15例,3级8例。缺损范围2.0～4.0cm2。Lysholm评分(69.54±12.36)分。结果术后切口Ⅰ期愈合。15例获随访,随访时间24～48个月,平均33个月。术后6个月12例关节症状完全消失;2例剧烈活动后关节出现肿胀,1例上下楼梯时前膝偶有酸痛不适,经对症治疗后痊愈。术后24个月Lysholm评分(94.15±9.21)分,与术前比较差异有统计学意义(P<0.05)。结论关节镜下OAT创伤小、能恢复关节面的曲度,是治疗小面积软骨缺损有效方法之一。
作者 皇甫小桥 赵金忠 杨星光
机构地区 上海交通大学附属第六人民医院关节镜外科
出处 《中国修复重建外科杂志》 CAS CSCD 北大核心 2008年第7期891-893,共3页 Chinese Journal of Reparative and Reconstructive Surgery
关键词 关节镜 膝关节 软骨缺损 自体骨软骨移植 修复
分类号 R687.34 [医药卫生—骨科学] R681.3 [医药卫生—骨科学]
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参考文献9

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  • 2Gudas R, Kalesinskas RJ, Kimtys V, et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy, 2005, 21(9): 1066-1075.
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同被引文献15

  • 1李晓宏,赵伟成,杨承祥.奥泰灵用于治疗膝骨关节炎的临床观察[J].中国疼痛医学杂志,2005,11(6):365-366. 被引量：16
  • 2刘瑞,孙官文,赵建民.玻璃酸钠与玻璃酸钠加地塞米松治疗膝骨关节炎的体会[J].内蒙古医学院学报,2006,28(2):125-126. 被引量：4
  • 3Marcacci M,Kon E,Zaffagnini S,et al.Multiple osteochondral arthroscopic grafting(mosaicplasty)for cartilage defects of the knee:prospective study results at2-year follow-up[J] .Arthroscopy,2005,21(4):462-470.
  • 4Robert H.Chondral repair of the knee joint using mosaicplasty[J] .Orthop Traumatol Surg Res,2011,97(4):418-429.
  • 5Ando W,Fujie H,Moriguchi Y,et al.Detection of abnormalities in the superficial zone of cartilage repaired using a tissue engineered construct derived from synovial stem cells[J] .Eur Cell Mater,2012,28(24):292-307.
  • 6Erickson IE,Kestle SR,Zellars KH,et al.High mesenchymal stem cell seeding densities in hyaluronic acid hydrogels produce engineered cartilage with native tissue properties[J] .Acta Biomater,2012,8(8):30273034.
  • 7Kono M,Takao M,Naito K,et al.Retrograde drilling for osteochondral lesions of the talar dome[J] .Am JSports Med,2006,34(9):1450-1460.
  • 8Hangody L,Vásárhelyi G,Hangody LR,et al.Autologous osteochondral grafting-technique and long-term results[J] .Injury,2008,39(Suppl1):S32-S39.
  • 9Visna P,Pasa L,Hart R,et al.Treatment of deepchondral defects of the knee using autologous chondrocytes cultured on a support--results after one year[J] .Acta Chir Orthop Traumatol Cech,2003,70(6):356362.
  • 10Chow JC,Hantes ME,Houle JB,et al.Arthroscopic autogenous osteochondral transplantation for treating knee cartilage defects:a2-to5-year follow-up study[J] .Arthroscopy,2004,20(7):681-690.

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二级引证文献14

中国修复重建外科杂志
2008年 第7期

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