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缬沙坦与氢氯噻嗪联合治疗高血压病疗效观察 被引量:4

CLINICAL OBSERVATION ON THE TREATMENT OF HYPERTENSION BY VALSARTAN COMBINED WITH HYDROCHLOROTHIAZIDE
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摘要 目的观察缬沙坦与氢氯噻嗪联合治疗原发性高血压的疗效。方法40例原发性高血压,患者服用缬沙坦80mg,每日1次;氢氯噻嗪12.5mg,每日1次,每周发放一次药物并测量血压。观察6周。结果①显效28例(70%),有效6例,无效6例,总有效率85%。②不良反应主要有血尿酸升高、干咳、头晕,均为轻度。结论缬沙坦与氢氯噻嗪联合治疗原发性高血压病疗效显著,且安全性良好。
作者 欧茂发
出处 《现代医院》 2008年第7期67-67,共1页 Modern Hospitals
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  • 1European Society of Hypertension - European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension - E - uropean society of Cardiology guidelines for the management of arterial hypertension [ J ]. Hypertens, 2003,21 : 1011 - 1053.
  • 2CHOBANIAN A V, BAKRIS G L, BLACK H B, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA ,2003,289:2560 - 2572.
  • 3FENICHEL R R, LIPICKY R J. Combination products as flint - line pha - rmacotherapy[ J ]. Arch Intern Med, 1994,154 : 1429 - 1430.

同被引文献25

  • 1李建英,郭进,黄国秀,温建东,陈健,余文珊.替米沙坦对老年高血压病患者胰岛素抵抗的影响[J].广西医科大学学报,2009,26(6):919-921. 被引量:1
  • 2李为民,刘巍.2005年中国高血压防治指南评介[J].中国实用内科杂志,2007,27(12):899-902. 被引量:73
  • 3Tamsma JT,Jazet IM,Beishuizen ED,et al. The metabolic sydrome:a vascular perspective [J]. Eur J Intern Med, 2005,16 (5) : 314-320.
  • 4Qin XP,Ye F,Liao DF,et al. Involvement of calciton in generelated peptide in depressor effects of losartan and perindopril in rats [J]. Eur J Pharmaeol, 2003,464 ( 1 ) : 63-67.
  • 5Uzu T,Nishimura M,Fujii T,et al. Benidipine attenuates glomerruler hypertension and reduces albuminuria in patients with metabolic syn- drome [J]. Hypertens Res, 2007,30 : 161-165.
  • 6Akizuki O,lnayoshi A,Kitayama T,et al. Blockade of T-type voltage-dependent Ca2+ channels by benidipine A dihydropyridine calcium chan- nel blocker,inhibits aldosterone production in human adrenocortical cell line NCI-H295 R [J]. Eur J Pharmacol, 2008,584 : 424-434.
  • 7Saito F,Fujita H,Takahashi A,et al. Renoprotective effect and cost-ef- fectiveness of using benidipine,a calcium channel blocker,to lower the dose of angiotensin receptor blocker in hypertensive patients with albu- minuria [J]. Hylxntens Res, 2007,30 : 39-47.
  • 8Hayashi K,Wakino S,Homma K,et al. Pathophysiological significance of T-type Ca2+ channel:role of T-type Ca2+ channel in renal microcircu- lation [J]..l Pharmacol Sci ,2005,99:221-227.
  • 9Gashti CN, Bakris GL. The role of calcium antagonists in chronic kidney disease [J]. Curr Opin Nephrol Hypertens,2004,13:155-161.
  • 10Matsuzaki G,Ishizaka N ,Furuta K,et al. Comparison of vasculoprotec-tive effects of benidipine and losartan in a rat model of metabolic syn- drome [J]. Eur J Pharmaeol,2008,587:237-242,.

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