摘要
目的:观察局部晚期食管癌外科手术前化疗的临床疗效。方法:研究组134例食管癌患者术前采用2个周期的顺铂加氟尿嘧啶的化疗方案,化疗后2周手术;对照组130例食管癌患者直接手术。结果:研究组116例患者肿瘤明显缩小,根治性切除112例,占83.6%;对照组根治性切除89例,占68.5%。两组对比差异有显著性(P<0.05)。结论:术前新辅助化疗可降低食管癌肿瘤分期、提高根治性切除率、并且可提高术后生存率。
Objective：To observe the clinical changes of local advanced esophageal carcinoma treated with new adjuvant chem-otherapy before operation and subsistence rate of pest operation. Methods： 134 cases with esophageal carcinoma take two periodic chemotherapy before operation. The other 130 cases take operation indirectly. Results： In the test group, the lengths of lesions for 116 cases reduced and 112 cases were resected entirely （83.6%）. In the other group, 89 cases were resected entirely （68.5%）. There were significant differences between the two groups. P 〈 0.05. Conclusions： New adjuvant chemotherapy could debase the stage of esophageal carcinoma, increase the resection rate and subsistence rate.
出处
《中国民康医学》
2008年第13期1419-1420,共2页
Medical Journal of Chinese People’s Health
关键词
食管癌
新辅助化疗
生存率
Esophageal carcinoma
New adjuvant chemotherapy
Subsistence rate
